Surface ozone and particulate matter are strongly influenced by both emissions and meteorological conditions. In the tropics such as Southeast Asia, the effect of climatic and emission factors on air pollution episodes such as the increased level of surface ozone and particulate matter is relatively unexplored. Understanding how the changes in climatic and emission factors affect the atmospheric chemistry, and subsequently on air pollution in the region, requires full understanding on the regional climate change and emission scenarios. This study is focusing on the investigation of how climate change, biomass and biogenic emissions influence the tropospheric chemistry that leads to the ozone and secondary aerosol formation in the region under different climate scenarios. Under the collaborative works of five countries, we are employing the high-resolution WRF model for the climate change projection under different Representative Concentration Pathways (RCPs), MEGAN for the biogenic emissions and CMAQ model for the air quality. The results of this investigation will be crucial in vulnerability and risk assessment exercises towards mitigation and adaptation policy formulation in respective countries in Southeast Asia that relate to wider issues such as climate change and greenhouse gases (GHGs), biomass emission and forest, biogenic emissions and land cover, and air quality and human health.