Since 1950, Southeast Asia has experienced warming temperature, changes in seasonal rainfall patterns, and the prevalence of extreme climatic events like drought and flood. In the Indochina peninsula, climatic hazards present serious threats to food security and livelihood of rural households (IPCC, 2014), especially those living in upland where poverty is always a problem (World Bank, 2017). Enhancing food security and adaptive capacity for this vulnerable population is a policy priority. Using the mixed method, this project will investigate factors influencing i) households’ adoption of climate change adaptation strategies and ii) the relationship between household’s climate change adaptation and food security in upland Laos, Cambodia, and Vietnam. 12 focus group discussions, then a survey of 750 households will be conducted in mountainous provinces in these countries. A Double Hurdle Model will be used to explain adaptation behaviour. An Ordered Logit Model that includes adaptation behaviour as one of the predictors will be applied to predict households’ food security status. This will be the first cross country research that quantifies the drivers and barriers to households’ climate change adaptation and food security in uplands of developing countries in Asia. Project findings will be useful for policymakers in developing countries and development agencies in designing interventions to enhance food security and resilience to climate change for vulnerable groups.