This study is designed to investigate farmers’ intentions to adopt climate-smart agricultural practices in response to climate change. This study particularly takes into consideration the psychological factors to assess adaptation intentions of farmers. Data were collected from 270 farmers from high attitude farming regions of Pakistan and Nepal using semi-structured interviews. The study uses the structural equation modeling (SEM) technique to explore the relationship between constructs. The findings of the study show that intention to adopt CSA practices increases with high-risk perceptions of climate change impacts on farmers’ livelihood. Similarly, adaptation intentions are positively related to greater effectiveness of adaptation measures (adaptation appraisal). In contrast, their belief regarding climate change does not make any significant influence on their adaptation intentions. Intentions to adopt CSA practices increases when farmers perceive greater support from government departments and perceive that government departments have the required expertise and capacity to support adaptation at a local level. However, disincentive such as an increase in prices of electricity, fertilizer, and fuel does not make any impact on their adaptation intentions. Further, habit and subjective norms of the farming household does significantly influence their adaptation intention and the use of certain smart practice at their farm.