Agriculture in South Asia is vulnerable to climate change. Therefore, adaptation measures are required to sustain agricultural productivity, reduce vulnerability, & enhance the resilience of the agricultural system to climate change. Absence of adaptation measures to climate change, South Asia could lose an equivalent of 1.8% of its annual gross domestic product (GDP) by 2050 & 8.8% by 2100 (Ahmed & Suphachalasai 2014). The present research analyses prevalent agricultural policies to map the policy-practice gaps at the bottom of social pyramid in India, Bangladesh, Sri Lanka & Pakistan to address the dual crisis, overviewing Intended Nationally Determined Contribution, Net Zero scenario, Global climate agendas etc. It intends to identify the synergies & trade-offs in policy-practice breaches through multi-criteria scenario planning & developing policy relevance for policy stakeholders at local, national, regional levels. Recommending adaptive policy framework, advocating nature-based solutions through knowledge economy is the overarching approach herein. Gender just approach includes awareness & capacity building of women farmers to help enhance their resilience. Knowledge dissemination would provide a platform & readiness of mind to grasp the cross-sectoral policy-practice scenario. Community input in policy framework design would make it realistic for adoption. Institutional networking facilitates the knowledge economy through regional workshops & policy brainstorming.