This paper introduces the process of development and practical use implementation of an advanced river management system for supporting integrated water resources management practices in Asian river basins under the framework of GEOSS Asia water cycle initiative (AWCI). The system is based on integration of data from earth observation satellites and in-situ networks with other types of data, including numerical weather prediction model outputs, climate model outputs, geographical information, and socio-economic data. The system builds on the water and energy budget distributed hydrological model (WEB-DHM) that was adapted for specific conditions of studied basins, in particular snow and glacier phenomena and equipped with other functions such as dam operation optimization scheme and a set of tools for climate change impact assessment to be able to generate relevant information for policy and decision makers. In situ data were archived for 18 selected basins at the data integration and analysis system of Japan (DIAS) and demonstration projects were carried out showing potential of the new system. It included climate change impact assessment on hydrological regimes, which is presently a critical step for sound management decisions. Results of such three case studies in Pakistan, Philippines, and Vietnam are provided here.