Natural ecosystems in Asia are expected to deteriorate in the coming decades due to pressures from climate change, and socioeconomic changes. The resultant impact can be resource insecurity, jeopardizing human wellbeing in this region. The loss of human wellbeing can lead to increased poverty and unsustainable land use practices, overexploitation and resource degradation. Unlocking the interlinkage between human wellbeing and ecosystem services can bring policy-relevant solutions in the region for a climate-smart, and integrated landscape based development. The information gained can have immense implications on Nationally Determined Contributions (NDCs) through landscape-level approaches. Accordingly, the research aims to analyze the interlinkage between ecosystem services and human wellbeing to bring local scale, climate-smart, and policy-relevant solutions for resource security. This research is based on an integrated assessment of ecosystem services and their interlinkage to human wellbeing through a participatory knowledge platform – involving local and scientific knowledge. The research is located in the realm of integrated landscape management, applying the concept of Ecosystem-based Adaptation (EbA) to address locally governed ‘climate-smart’ landscapes with low carbon society and multiple ecosystem services.