Food production is one of the major human activities for the temperate northeast Asia, including north China, Mongolia, and southeast Russia, and plays a crucial role in local socio-economic development. Water scarcity and land degradation have put the local sustainable agriculture development in great danger due to climate change and intensified human activities, seriously threatening regional water and food security. The main objective of this comprehensive research project is to develop an integrated model system to assess the potential mitigation options and sustainable development opportunities in relation to water and food security at local scale, providing the policy-makers the needed information to achieve regional sustainable development. It also aims building capacity and raising awareness through participatory assessment and the dissemination of the project findings and model.